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> FACIT Development and Validation References

Cella, D.F., Tulsky, D.S., Gray, G., Sarafian, B., Lloyd, S., Linn, E., Bonomi, A., Silberman, M., Yellen, S.B., Winicour, P., Brannon, J., Eckberg, K., Purl, S., Blendowski, C., Goodman, M., Barnicle, M., Stewart, I., McHale, M., Bonomi, P., Kaplan, E., Taylor, S., Thomas, C., & Harris, J. (1993). The Functional Assessment of Cancer Therapy (FACT) scale: Development and validation of the general measure. Journal of Clinical Oncology, 11(3), 570-579.

 

Webster, K., Odom, L., Peterman, A., Lent, L., & Cella, D. (1999).  The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Validation of version 4 of the core questionnaire. Quality of Life Research, 8(7), 604.

 

Winstead-Fry, P., & Schultz, A. (1997). Psychometric assessment of the Functional Assessment of Cancer Therapy-General (FACT-G) scale in a rural sample. Cancer, 79(12), 2446-2452.

 

Overcash, J., Extermann, M., Parr, J., Perry, J., & Balducci, L. (2001). Validity and reliability of the FACT-G scale for use in the older person with cancer. American Journal of Clinical Oncology, 24(6), 591-596.

 

Webster, K., Cella, D., & Yost, K. (2003). The Functional Assessment of Chronic Illness Therapy (FACIT) Measurement System: Properties, applications, and interpretation. Health and Quality of Life Outcomes, 1, 79.

 

FACT-GP (General Population):

Cella, D., Zagari, M., Vandoros, C., Gagnon, D., Hurtz, H., & Nortier, J. (2002c). Epoetin Alfa treatment results in clinically significant improvements in quality of life in anemic cancer patients when referenced to the general population. Journal of Clinical Oncology, 21, 366-373.


 

Cancer Specific Measures:


 

FACT-B (Breast):

Brady, M.J., Cella D.F., Mo, F., Bonomi, A.E., Tulsky, D.S., Lloyd, S.R., Deasy, S., Cobleigh M., & Shiomoto, G. (1997). Reliability and validity of the Functional Assessment of Cancer Therapy-Breast (FACT-B) quality of life instrument. Journal of Clinical Oncology, 15, 974-986.

 


FACT-Br (Brain): 

Weitzner, M.A., Meyers, C.A., Gelke, C., Byrne, K., Cella, D.F., & Levin, V.A. (1995). The Functional Assessment of Cancer Therapy (FACT) scale: Development of a brain subscale and revalidation of the general version (FACT-G) in patients with primary brain tumors. Cancer, 75(5), 1151-1161. 

 

FACT-C (Colorectal):

Ward, W.L., Hahn, E.A., Mo, F., Hernandez, L., Tulsky, D.S., & Cella, D. (1999). Reliability and validity of the Functional Assessment of Cancer Therapy-Colorectal (FACT-C) quality of life instrument. Quality of Life Research, 8(3), 181-195.

 

Yost, K., Eton, D., Cella, D., Ayanian, J., Zaslavsky, A., & Dee West.  (2002).  Minimal Important Differences on the Functional Assessment of Cancer Therapy – Colorectal.  Quality of Life Research, 11, (7), 629.

 

FACT-Ga (Gastric): 

Eremenco, S., Cashy, J., & Webster, K.  (2003). Linguistic validation of the FACT-Gastric (FACT-Ga) in Japanese and English. Quality of Life Research, 12(7), 818.

 

FACT-HN (Head and Neck): 

List, M.A., D’Antonio, L.L., Cella, D.F., Siston, A., Mumby, P., Haraf, D., & Vokes, E. (1996). The Performance Status Scale for head and neck cancer patients and the Functional Assessment of Cancer Therapy-Head and Neck (FACT-H&N) scale: A study of utility and validity. Cancer, 77, 2294-2301.

 

D’Antonio, L.L., Zimmerman, G.J., Cella, D.F., & Long, S.A. (1996). Quality of life and functional status measures in patients with head and neck cancer. Archives of Otolaryngol Head & Neck Surgery, 122, 482-487.

 

FACT-Hep (Hepatobiliary): 

Heffernan, N., Cella, D., Webster, K., Odom, L., Marone, M., Passik, S., Bookbinder, M., Fong, Y., Jarnagin, W., Blumbart, L. (2002). Measuring health-related quality of life in patients with hepatobiliary cancers: The Functional Assessment of Cancer Therapy - Hepatobiliary (FACT-Hep) questionnaire. Journal of Clinical Oncology, 20(9), 2229-2239.

 

FHSI (FACT-Hep Symptom Index):

Yount, S., Cella, D., Webster, K., Heffernan, N., Chang, C.H., Odom, L., van Gool, R. (2002). Assessment of patient-reported clinical outcome in pancreatic and other hepatobiliary cancers: The FACT Hepatobiliary Symptom Index. Journal of Pain and Symptom Management, 24(1), 32-44.

 

Cella D., Webster, K., Chang, C.H., Odom, L., Heffernan, N., & van Goo,l R. (2000). Deriving a clinically meaningful symptom index from the Functional Assessment of Cancer Therapy-Hepatobiliary (FACT-Hep) Scale: The FHSI-8. Quality of Life Research, 9 (3), 293 (Abstract #1591).

 

Yount, S., Cella, D., Paul, D., Winn, R., Chang, C.-H., Weeks, J., Banik, D., Heffernan, N., Webster, K., van Gool, R., & Odom, L. (2001).  Rapid assessment of patient-reported symptoms in advanced cancers. Quality of Life Research, 10 (3), 212.

 

FACT-L (Lung):

Cella, D.F., Bonomi, A.E., Lloyd S.R., Tulsky, D.S., Kaplan, E., & Bonomi, P. (1995). Reliability and validity of the Functional Assessment of Cancer Therapy - Lung (FACT-L) quality of life instrument. Lung Cancer, 12, 199-220.

 

Cella, D., Eton, D., Fairclough, D.L., Bonomi, P., Heyes, A., Silberman, C., Wolf, M.K., & Johnson, D.H. (2002). What is a clinically meaningful change on the Functional Assessment of Cancer Therapy-Lung (FACT-L) questionnaire? Results from Eastern Cooperative Oncology Group (ECOG) Study 5592. Journal of Clinical Epidemiology, 55, 285-295.

 

Cella, D.F., Bonomi, A.E., Lloyd S., Tulsky, D., Bonomi, P., & Kaplan, E. (1994). Reliability and validity of the Functional Assessment of Cancer Therapy-Lung (FACT-L) quality of life instrument. Lung Cancer, 11(Suppl 1), 89 (Abstract #336).

 

Cella, D.F. (1995). The Functional Assessment of Cancer Therapy-Lung (FACT-L) quality of life instrument. In R.J. Gralla & C.M. Moinpour (Eds): Assessing Quality of Life in Patients with Lung Cancer: A Guide for Clinicians. New York: NCM Publishers, Inc.

 

Butt, Z., Webster, K., Eisenstein, A.R., Beaumont, J., Eton, D., Masters, G.A., & Cella, D. (2005). Quality of life in lung cancer: The validity and cross-cultural applicability of the Functional Assessment of Cancer Therapy-Lung scale. Hematol Oncol Clin N Am, 19, 389-420.

 

FACT-Leu (Leukemia):

Webster, K., Chivington, K., Shonk, C., Eremenco, S., Yount, S., Hahn, E., van Gool, R., Tallman, M., & Cella, D. (2002).  Measuring quality of life (QOL) among patients with leukemia: The Functional Assessment of Cancer-Therapy-Leukemia (FACT-Leu). Quality of Life Research, 11(7), 678.

 

FACT-Lym (Lymphoma):

Eremenco, S., Webster, K., Kutikova, L., Bowman, L., & Cella D. (2004). Development and multilingual validation of the FACT-Lymphoma Instrument. Quality of Life Research, 13(9), 1501.

 

Webster K, Cashy J, Cella D, Kutikova L, Gauthier J, Liepa A, Bowman L, & Gregory S.  Measuring quality of life (QOL) in patients with non-Hodgkin’s Lymphoma (NHL): The Functional Assessment of Cancer Therapy-Lymphoma (FACT-Lym). (2005). Quality of Life Research, 14(9), 1650.

 

Cella D, Webster K, Cashy J, Kutikova L, Burgess MF, Lin BK, Bowman L, Liepa AM, Gauthier JE, Gregory SA, Johnson SA, and Bruce D. Cheson on Behalf of the FACT-Lym Development Group. Development of a Measure of Health-Related Quality of Life for Non-Hodgkin’s Lymphoma Clinical Research: The Functional Assessment of Cancer Therapy - Lymphoma (FACT-Lym).Blood (ASH Annual Meeting Abstracts), Nov 2005; 106: 750.

 

FACT-M (Melanoma):

Cormier, J., Davidson, L., Xing, Y., Webster, K., & Cella, D. (2005). Measuring quality of life in patients with melanoma: Development of the FACT-Melanoma Subscale.  The Journal of Supportive Oncology, 3(5), 139-145.

 

FACT-O (Ovarian):

Basen-Enquist, K., Bodurka-Bevers, D., Fitzgerald, M.A., Webster, K., Cella, D., Hu, S., & Gershenson D.M. (2001). Reliability and validity of the Functional Assessment of Cancer Therapy-Ovarian (FACT-O). Journal of Clinical Oncology, 19(6), 1809-1817.

 

FACT-P (Prostate):

Esper, P., Mo, F., Chodak, G., Sinner, M., Cella, D., & Pienta, K.J. (1997). Measuring quality of life in men with prostate cancer using the Functional Assessment of Cancer Therapy-Prostate (FACT-P) instrument. Urology, 50(6), 920-928.

 

Esper, P., Pienta, K., & Cella, D. (1995). FACT-P: A new instrument for quality of life evaluation in prostate cancer. Proceedings of the American Urological Association 1995 Annual Meeting, Las Vegas, NV.

 

Esper, P., Pienta, K., & Cella, D. (1995). Development of a new instrument for measuring quality of life in patients undergoing therapy for prostate cancer. Proceedings of the Association for the Advancement of Cancer Research 1995 Meeting.


 

FACT-V (Vulvar):

Janda, M., Obermair, A., Cella, D., Crandon, A.J., & Trimmel, M. (2004). Vulvar cancer patients’ quality of life: A qualitative assessment. International Journal of Gynecological Cancer, 14, 875-881.