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Functional Assessment of Cancer Therapy - Bone Marrow Transplantation

For patients undergoing Bone Marrow Transplantation



Below are the details for the FACT-BMT measure:


Functional Assessment of Cancer Therapy - Bone Marrow Transplantation (FACT-BMT)






Cancer patients 18 years and older undergoing bone marrow transplantation


Past 7 days


5 point Likert-type scale


Paper and electronic


Self-administration and interview when applicable


Physical Well-Being, Social/Family Well-Being, Emotional Well-Being, Functional Well-Being, Bone Marrow Transplantation Subscale


10-15 minutes


Manual scoring template, some items are reverse scored. Subscale scores, total scores and TOI scores possible. SAS/SPSS algorithms available.


Language Availability

Available translations of the FACT-BMT can be obtained by registering for permission. Users are not permitted to translate the FACT-BMT without permission from Permission from to translate the FACT-BMT may also be contingent upon timeline expectations and availability of FACIT staff. Translations must undergo a rigorous methodology under the guidance of which includes multiple translators, QA steps and cognitive interviews with patients. For commercial use, FACITtrans is the approved translation vendor to translate the FACIT measurement system.

Please contact us for more information.

Language Availability


Licensing fees are assessed on a per trial/per measure basis for commercial use. There is no fee for use of the English version, but a license should be obtained.

Non-commercial use is assessed on a case-by-case basis. Licensing fees are typically not applied to investigator-initiated research, students, or clinical use.

To license an available version of this measure for commercial or non-commercial use, please complete our registration form. All of the information provided in the form will be kept strictly confidential. For questions, please contact us.

Selected References

Selected References

Bieri, S., Roosnek, E., Helg, E., Verholen, F., Robert, D., Chapuis, B., Passweg, J., Miralbell, R., & Chalandon, Y.  Quality of life and social integration after allogeneic hematopoietic SCT.  Bone Marrow Transplantation 2008; 42: 819–827.  doi:10.1038/bmt.2008.253.

Cohen, M., Rozmus, C., Mendoza, T., Padhye, N., Neumann, J., Gning, I., Aleman, A.., Giralt, S., & Cleeland, C.  Symptoms and Quality of Life in Diverse Patients Undergoing Hematopoietic Stem Cell Transplantation.  Journal of Pain and Symptom Management 2012; 44(2): 168-180. doi:10.1016/j.jpainsymman.2011.08.011. 

Heinonen, H.,  Volin, L., Uutela, A., Zevon, M. Barrick, C.,&  Ruutu, T.  Quality of life and factors related to perceived satisfaction with quality of life after allogeneic bone marrow transplantation.  Ann Hematol 2001; 80: 137–143..  doi: 10.1007/s002770000249.

Herzberg, P., Lee, S., Heussner, P., Mumm, F. Hilgendorf, I., von Harsdorf, S., Hemmati, P., Rieger, K., Greinix, H., Freund, M., Holler, E., & Wolff, D.  Personality influences quality-of-life assessments in adult patients after allogeneic hematopoietic SCT: results from a joint evaluation of the prospective German Multicenter Validation Trial and the Fred Hutchinson Cancer Research Center.  Bone Marrow Transplantation 2013; 48: 129–134. doi:10.1038/bmt.2012.83. 

Kopp M, Schweigko¯er H, Holzner B, Nachbaur D, Niederwieser D, Fleischhacker W, Kemmler G, Sperner-Unterweger B.  EORTC QLQC30 and FACT-BMT for the measurement of quality of life in bone marrow transplant recipients: a comparison.  European Journal of Haematology 2000; 65: 97-03.

Lau, A., Chang, C., Tai, J., Eremenco, S., Liang, R., Lie, A., Fong, D., & Lau, C.  Translation and validation of the Functional Assessment of Cancer Therapy–Bone Marrow Transplant (FACT-BMT) Version 4 quality of life instrument into traditional Chinese.  Bone Marrow Transplantation 2002; 29: 41–49.  doi: 10.1038/sj/bmt/1703313.

McQuellon, R.P., Russell, G.B., Cella, D.F., Craven, B.L., Brady, M., Bonomi, A., & Hurd, D.D.  Quality of life measurement in bone marrow transplantation:  Development of the Functional Assessment of Cancer Therapy - Bone Marrow Transplant (FACT-BMT) scale.  Bone Marrow Transplantation 1997; 19: 357-368.

McQuellon, R., Russell, G., Rambo, T., Craven, B., Radford, J., Perry, J., Cruz, J., & Hurd, D.  Quality of life and psychological distress of bone marrow transplant recipients: the ‘time trajectory’ to recovery over the first year.  Bone Marrow Transplantation 1998; 21: 477–486.  

Pidala, J., Kurland, B., Chai, X., Vogelsang, G., Weisdorf, D., Pavletic,S., Cutler, C., Majhail,N., & Lee, S.  Sensitivity of changes in chronic graft-versus-host disease activity to changes in patient-reported quality of life: results from the Chronic Graft-versus-Host Disease Consortium.  Hematologica 2011; 96(10): 1528-1535. doi: 10.3324/haematol.2011.046367. 

Bonomi, A.E., Cella, D.D., Hahn, E.A., Bjordal, K., Sperner, B., Gangeri, L., Bergman, B., Willems, J., Hanquet, P., & Zittoun, R.  Multilingual translation of the Functional Assessment of Cancer Therapy (FACT) quality of life measurement system.  Quality of Life Research 1996; 5: 309-320.

Eremenco, S., Arnold, B., Cella, D. A comprehensive method for the translation and cross-cultural validation of health status questionnaires. Evaluation & the Health Professions 2005; 28(2): 212-232.

Webster K., Cella D., Yost K. The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Properties applications, and interpretation. Health and Quality of Life Outcomes 2003; 1(1): 79-85.

Yost K.J., Eton D.T. Combining distribution- and anchor-based approaches to determine minimally important differences: The FACIT experience. Evaluation & the Health Professions 2005; 28(2): 172-191.

Related Measures

Related Measures


Functional Assessment of Cancer Therapy - Biologic Response Modifiers


Functional Assessment of Cancer Therapy/Gynecologic Oncology Group – Neurotoxicity


Functional Assessment of Cancer Therapy - Bone Pain

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