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FACT-O

Functional Assessment of Cancer Therapy – Ovarian

For patients with Ovarian cancer

Overview

Overview

The Functional Assessment of Cancer Therapy – Ovarian (FACT-O) provides a reliable and valid assessment of the quality of life of women with ovarian cancer, and is appropriate as a brief quality of life assessment in clinical trials and descriptive studies. It was initially validated with 232 ovarian cancer patients attending an outpatient gynecologic oncology clinic, who completed the measure at baseline. The patients’ FACT-O scores were then compared with their performance status, disease stage, treatment status, and other factors hypothesized to be related to quality of life. Patients received a second measure either one week after baseline to assess the instrument’s test-retest reliability and/or two months after baseline to evaluate its sensitivity to change in performance status. Overall, the subscales correlated with other measures as expected; all correlations were in the hypothesized direction. Patients with advanced disease, poor performance status, and who were receiving active treatment had lower scores on physical, functional, and ovarian cancer-specific scales. The total FACT-O and emotional well-being scores were lower for patients with poor performance status and patients in active treatment. The FACT-O total and all subscale scores except emotional well-being were sensitive to decreases in performance status.

MEASURE NAME:

Functional Assessment of Cancer Therapy – Ovarian (FACT-O)

VERSION:

4

NUMBER OF ITEMS:

39

PATIENT POPULATION:

Ovarian cancer patients 18 years and older

RECALL PERIOD:

Past 7 days

RESPONSE SCALE:

5 point Likert-type scale

DATA COLLECTION:

Paper and electronic

ADMINISTRATION:

Self-administration and interview when applicable

SUBSCALE DOMAINS:

Physical Well-Being, Social/Family Well-Being, Emotional Well-Being, Functional Well-Being, Ovarian Cancer Subscale

TIME FOR COMPLETION:

10-15 minutes

SCORING:

Manual scoring template, some items are reverse scored. Subscale scores, total scores and TOI scores possible. SAS/SPSS algorithms available.

RELATED MEASURES:

Language Availability

Available translations of the FACT-O can be obtained by registering for permission. Users are not permitted to translate the FACT-O without permission from FACIT.org. Permission from FACIT.org to translate the FACT-O may also be contingent upon timeline expectations and availability of FACIT staff. Translations must undergo a rigorous methodology under the guidance of FACIT.org which includes multiple translators, QA steps and cognitive interviews with patients. For commercial use, FACITtrans is the approved translation vendor to translate the FACIT measurement system.

Please contact us for more information.

Language Availability
Licensing

Licensing

Licensing fees are assessed on a per trial/per measure basis for commercial use. There is no fee for use of the English version, but a license should be obtained.

Non-commercial use is assessed on a case-by-case basis. Licensing fees are typically not applied to investigator-initiated research, students, or clinical use.

To license an available version of this measure for commercial or non-commercial use, please complete our registration form. All of the information provided in the form will be kept strictly confidential. For questions, please contact us.

Selected References

Selected References

Basen-Engquist, K., Bodurka-Bevers D., Fitzgerald M., Webster K., Cella D., Hu S., & Gershenson D. Reliability and Validity of the Functional Assessment of Cancer Therapy-Ovarian.  The Journal of Clinical Oncology 2001; 19(6): 1809-1817.  doi: 10.1200/jco.2001.19.6.1809.


Bonomi, A.E., Cella, D.D., Hahn, E.A., Bjordal, K., Sperner, B., Gangeri, L., Bergman, B., Willems, J., Hanquet, P., & Zittoun, R.  Multilingual translation of the Functional Assessment of Cancer Therapy (FACT) quality of life measurement system.  Quality of Life Research 1996; 5: 309-320.


Eremenco, S., Arnold, B., Cella, D. A comprehensive method for the translation and cross-cultural validation of health status questionnaires. Evaluation & the Health Professions 2005; 28(2): 212-232.


Webster K., Cella D., Yost K. The Functional Assessment of Chronic Illness Therapy (FACIT) measurement system: Properties applications, and interpretation. Health and Quality of Life Outcomes 2003; 1(1): 79-85.


Yost K.J., Eton D.T. Combining distribution- and anchor-based approaches to determine minimally important differences: The FACIT experience. Evaluation & the Health Professions 2005; 28(2): 172-191.

Related Measures

Related Measures

FOSI

Functional Assessment of Cancer Therapy Ovarian Cancer Symptom Index - 8 Item Version

NFOSI-18

National Comprehensive Cancer Network/Functional Assessment of Cancer Therapy Ovarian Cancer Symptom Index - 18 Item Version

FACT-Cx

Functional Assessment of Cancer Therapy – Cervix

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