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PROMIS SF v1.0 Fatigue 10a

Patient Reported Outcomes Measurement Information System - Short Form - Fatigue 10a

10 item PROMIS adoption of the FACIT-Fatigue



The PROMIS SF v1.0 Fatigue 10a is the adapted, shortened version of the FACIT-Fatigue from the PROMIS Health Organization.


PROMIS SF v1.0 Fatigue 10a






Patients 18 years and older experiencing fatigue


Past 7 days


5 point Likert-type scale


Paper and electronic


Self-administration and interview when applicable




Less than 5 minutes


Language Availability

Available translations of the PROMIS SF v1.0 Fatigue 10a can be obtained by registering for permission. Users are not permitted to translate the PROMIS SF v1.0 Fatigue 10a without permission from Permission from to translate the PROMIS SF v1.0 Fatigue 10a may also be contingent upon timeline expectations and availability of FACIT staff. Translations must undergo a rigorous methodology under the guidance of which includes multiple translators, QA steps and cognitive interviews with patients. For commercial use, FACITtrans is the approved translation vendor to translate the FACIT measurement system.

Please contact us for more information.

Language Availability


Licensing fees are assessed on a per trial/per measure basis for commercial use. There is no fee for use of the English version, but a license should be obtained.

Non-commercial use is assessed on a case-by-case basis. Licensing fees are typically not applied to investigator-initiated research, students, or clinical use.

To license an available version of this measure for commercial or non-commercial use, please complete our registration form. All of the information provided in the form will be kept strictly confidential. For questions, please contact us.

Selected References

Selected References

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Cella DF.  Factors Influencing Quality of Life in Cancer Patients: Anemia and Fatigue. Seminars in Oncology 1998; 25(3):43-46.  

Cella D, Yount S, Sorensen M, Chartash E, Sengupta N, Grober J. Validation of the Functional Assessment of Chronic Illness Therapy Fatigue Scale relative to other instrumentation in patients with rheumatoid arthritis. Journal of Rheumatology 2005; 32(5):811-9.

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Cella DF, Lai J, Chang C, Peterman A, Slavin M. Fatigue in cancer patients compared with fatigue in the general United States population. Cancer 2002; 94(2):528-538.  

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Cella DF and Webster K. Linking outcomes management to quality-of-life measurement. Oncology 1997; 11(11A):232-235.  

Cella DF, Zagari MJ, Vandoros C, Gagnon DD, Hurtz HJ, Nortier JWR.  Epoetin alfa treatment results in clinically significant improvements in quality of life in anemic cancer patients when referenced to the general population. Journal of Clinical Oncology 2003; 21(2):366-373. 

Chandran V, Bhella S, Schentag CT, Gladman DD.  Functional assessment of chronic illness therapy-fatigue scale is valid in patients with psoriatic arthritis. Annals of the Rheumatic Diseases 2007; 66(7):936-9.

Chang C-H, Bresnahan B, Gagnon D, Zagari M, McNulty P, Vercammen E, Georgoulias V, Husseini F, Cella D. Testing the validity of pooling multilingual health-related quality of life data from a multinational trial of Epoetin alfa in anemic cancer patients receiving nonplatinum-based chemotherapy. Unpublished manuscript.

Chang CH, Cella D, Clarke S, Heinemann AW, Von Roenn JH, Harvey R. Should symptoms be scaled for intensity, frequency, or both?. Palliative & Supportive Care 2003; 1(1):51-60.

Chang J, Couture F, Young S, McWatters KL, Lau CY. Weekly epoetin alfa maintains hemoglobin, improves quality of life, and reduces transfusion in breast cancer patients receiving chemotherapy. Journal of Clinical Oncology 2005; 23(12):2597-605.

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Courneya KS, Friedenreich CM, Sela RA, Quinney HA, Rhodes RE, Handman M. The group psychotherapy and home-based physical exercise (group-hope) trial in cancer survivors: physical fitness and quality of life outcomes. Psycho-Oncology 2003; 12(4):357-74.

Crawford J, Cella DF, Cleeland CS, Cremieux P, Demetri GD, Sarokhan BJ, Slavin MB, Glaspy JA.  Relationship between changes in hemoglobin level and quality of life during chemotherapy in anemic cancer patients receiving epoetin alfa therapy. Cancer 2002; 95(4):888-895.  

Dahele M, Skipworth RJ, Wall L, Voss A, Preston T, Fearon KC.  Objective physical activity and self-reported quality of life in patients receiving palliative chemotherapy. Journal of Pain & Symptom Management 2007; 33(6):676-685.

Demetri GD, Kris M, Wade J, Degos L, Cella DF. Quality-of-life benefit in chemotherapy patients treated with epoetin alfa is independent of disease response or tumor type: results from a prospective community oncology study. Journal of Clinical Oncology 1998; 16(10):3412-3425.  

Dubois D, Dhawan R, van de Velde H, Esseltine D, Gupta S, Viala M, de la Loge C. Descriptive and prognostic value of patient-reported outcomes: the bortezomib experience in relapsed and refractory multiple myeloma. Journal of Clinical Oncology 2006; 24(6):976-82.

Eremenco, S., Arnold, B., Cella, D. A comprehensive method for the translation and cross-cultural validation of health status questionnaires. Evaluation & the Health Professions 2005; 28(2): 212-232.

Fairclough DL, Gagnon DD, Zagari MJ, Marschner N, Dicato M. Epoetin Alfa Study Group. Evaluation of quality of life in a clinical trial with nonrandom dropout: the effect of epoetin alfa in anemic cancer patients. Quality of Life Research 2003; 12(8):1013-27.

Fallowfield L, Gagnon D, Zagari M, Cella D, Bresnahan B, Littlewood TJ, McNulty P, Gorzegno G, Freund M. Epoetin Alfa Study Group. Multivariate regression analyses of data from a randomised, double-blind, placebo-controlled study confirm quality of life benefit of epoetin alfa in patients receiving non-platinum chemotherapy. British Journal of Cancer 2002; 87(12):1341-53.

Fan HG, Houede-Tchen N, Yi QL, Chemerynsky I, Downie FP, Sabate K, Tannock IF. Fatigue, menopausal symptoms, and cognitive function in women after adjuvant chemotherapy for breast cancer: 1- and 2-year follow-up of a prospective controlled study. Journal of Clinical Oncology 2005; 23(31):8025-32.

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Gabrilove JL, Cleeland CS, Livingston RB, Sarokhan B, Winer E, Einhorn LH.  Clinical evaluation of once-weekly dosing of epoetin alfa in chemotherapy patients: improvements in hemoglobin and quality of life are similar to three-times-weekly dosing. Journal of Clinical Oncology 2001; 19(11):2875-2882.  

Genovese MC, Han C, Keystone EC, Hsia EC, Buchanan J, Gathany T, Murphy FT, Wu Z, Parasuraman S, Rahman MU. Effect of golimumab on patient-reported outcomes in rheumatoid arthritis: results from the GO-FORWARD study. J Rheumatol 2012; 39:1185-1191.

Gladman DD, Mease PJ, Cifaldi MA, Perdok RJ, Sasso E, Medich J.  Adalimumab improves joint-related and skin-related functional impairment in patients with psoriatic arthritis: patient-reported outcomes of the Adalimumab Effectiveness in Psoriatic Arthritis Trial. Annals of the Rheumatic Diseases 2007; 66(2):163-8.

Glaspy J, Degos L, Dicato M, Demetri GD.  Comparable efficacy of epoetin alfa for anemic cancer patients receiving platinum- and nonplatinum-based chemotherapy: a retrospective subanalysis of two large, community-based trials. Oncologist 2002; 7:126-135.  

Glaspy JA, Jadeja JS, Justice G, Kessler J, Richards D, Schwartzberg L, Tchekmedyian NS, Armstrong S, O’Byrne J, Rossi G, Colowick AB.  Darbepoetin alfa given every 1 or 2 weeks alleviates anaemia associated with cancer chemotherapy. British Journal of Cancer 2002; 87:268-276.  

Godino C, Jodar L, Duran A, Martinez I, Schiaffino A. Nursing education as an intervention to decrease fatigue perception in oncology patients. European Journal of Oncology Nursing 2006; 10(2):150-5.

Goligher EC, Pouchot J, Brant R, Kherani RB, Avina-Zubieta JA, Lacaille D, Lehman AJ, Ensworth S, Kopec J, Esdaile JM, Liang MH. Minimal clinically important difference for 7 measures of fatigue in patients with systemic lupus erythematosus. J Rheumatol 2008; 35(4):635-642.

Graziano F, Bisonni R, Catalano V, Silva R, Rovidati S, Mencarini E, Ferraro B, Canestrari F, Baldelli AM, De Gaetano A, Giordani P, Testa E, Lai V. Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients. British Journal of Cancer 2002; 86(12):1854-7.

Hagell P, Hoglund A, Reimer J, Eriksson B, Knutsson I, Widner H, Cella D.  Measuring fatigue in Parkinson's disease: a psychometric study of two brief generic fatigue questionnaires. Journal of Pain & Symptom Management 2006; 32(5):420-32.

Hagell P, Rosblom T, Palhagen S. A Swedish version of the 16-item Parkinson fatigue scale (PFS-16). Acta Neurol Scand 2012; 125:288-292.

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Hahn EA, Rao D, Cella D, Choi SW. Comparability of interview- and self-administration of the Functional Assessment of Cancer Therapy – General (FACT-G) in English- and Spanish- speaking ambulatory cancer patients. Medical Care 2008; 46(4):423-31.

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Hillmen P, Young NS, Schubert J, Brodsky RA, Socie G, Muus P, Roth A, Szer J, Elebute MO, Nakamura R, Browne P, Risitano AM, Hill A, Schrezenmeier H, Fu CL, Maciejewski J, Rollins SA, Mojcik CF, Rother RP, Luzzatto L. The complement inhibitor eculizumab in paroxysmal nocturnal hemoglobinuria. New England Journal of Medicine 2006; 355(12):1233-43.

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Macdonald JH, Fearn L, Jibani M, Marcora SM. Exertional fatigue in patients with CKD. Am J Kidney Dis 2012; 60(6):930-939.

Mallinson T, Cella D, Cashy J, Holzner B. Giving meaning to measure: linking self-reported fatigue and function to performance of everyday activities. Journal of Pain & Symptom Management 2006; 31(3):229-41.

Mar Fan HG, Clemons M, Xu W, Chemerynsky I, Breunis H, Braganza S, Tannock IF. A randomized, placebo-controlled, double-blind trial of the effects fo d-methylphenidate on fatigue and cognitive dysfunction in women undergoing adjuvant chemotherapy for breast cancer. Supportive Care in Cancer 2008; 16(6):577-83.

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Rajagopal A, Vassilopoulou-Sellin R, Palmer JL, Kaur G, Bruera E. Symptomatic hypogonadism in male survivors of cancer with chronic exposure to opioids. Cancer 2004; 100(4):851-8.

Reddy S, Bruera E, Pace E, Zhang K, Reyes-Gibby CC. Clinically important improvement in the intensity of fatigue in patients with advanced cancer. Journal of Palliative Medicine 2007; 10(5):1068-75.

Reese JB, Shelby RA, Abernethy AP. Sexual concerns in lung cancer patients: an examination of predictors and moderating effects of age and gender. Support Care Cancer 2011; 19:161-165.

Revicki DA, Rentz AM, Luo MP, Wong RL. Psychometric characteristics of the short form 36 health survey and functional assessment of chronic illness therapy – fatigue subscale for patients with ankylosing spondylitis. Health Qual Life Outcomes 2011; 9:36.

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Rizzo JD, Lichtin AE, Woolf SH, Seidenfeld J, Bennett CL, Cella DF, Djulbegovic B, Goode MJ, Jakubowski AA, Lee SJ, Miller CB, Rarick MU, Regan DH, Browman GP, Gordon MS. Use of epoetin in patients with cancer: evidence-based clinical practice guidelines of the American Society of Clinical Oncology and the American Society of Hematology. Journal of Clinical Oncology 2002; 20(19):4083-4107.  

Savonije JH,  van Groeningen CJ,  Wormhoudt LW,  Giaccone G. Early intervention with epoetin alfa during platinum-based chemotherapy: an analysis of the results of a multicenter, randomized, controlled trial based on initial hemoglobin level. Oncologist 2006; 11(2):206-16.

Savonije JH, van Groeningen CJ, Wormhoudt LW, Giaccone G. Early Intervention with epoetin alfa during platinum-based chemotherapy: an analysis of quality-of-life results of a multicenter, randomized, controlled trial compared with population normative data. Oncologist 2006; 11(2):197-205.

Shafqat A, Einhorn LH, Hanna N, Sledge GW, Hanna A, Juliar BE, Monahan P, Bhatia S. Screening studies for fatigue and laboratory correlates in cancer patients undergoing treatment. Annals of Oncology 2005; 16(9):1545-50.

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Smith E, Lai JS, Cella D. Building a measure of fatigue: the Functional Assessment of Chronic Illness Therapy Fatigue Scale. PM&R 2010; 2(5):359-363.

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Related Measures

Related Measures


Functional Assessment of Chronic Illness Therapy – Fatigue


Functional Assessment of Cancer Therapy – Fatigue


Functional Assessment of Cancer Therapy – Anemia

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